Vaccine-related Publications

Luck S, Torry M, d'Agapeyeff K, Pitt A, Heath PT, Breathnach A, Bedford Russell A. Estimated early-onset group B streptococcal neonatal disease. Lancet 2003; 361:1953-4.


Ramsay ME, McVernon J, Andrews NJ, Heath PT, Slack MP. Estimating Hib vaccine effectiveness in England and Wales using the screening method. J Infect Dis 2003;188:481-5.


Heath PT, Balfour G, Weisner AM, Efstratiou A, Lamagni TL, Tighe H, O'Connell LAF, Cafferkey M, Verlander NQ, Nicoll A, AC McCartney. Group B streptococcal disease in UK and Irish infants < 90 days of age. Lancet 2004;363:292-4.


Rothstein, E.; Kohl, K. S.; Ball, L.; Halperin, S. A.; Halsey, N.; Hammer, S. J.; Heath, P. T.; Hennig, R.; Kleppinger, C.; Labadie, J.Nodule at injection site as an adverse event following immunization: case definition and guidelines for data collection, analysis, and presentation. Vaccine 2004;22: 575-585.


Weisner AM, Johnson AP, Lamagni TL, Arnold E, Warner M, Heath PT, Efstratiou A. Characterisation of Group B Streptococci from Infants with Invasive Disease in England and Wales. Clinical Infectious Disease 2004;38:1203-8.


Collins C L, Ruggeberg JU, Balfour G, Tighe H, Archer M, Bowen-Morris J, Diggle L, Borrow R, Balmer P, Buttery J P, Moxon E R, Pollard AJ, Heath P T. Immunogenicity and Immunological Memory of Meningococcal C Conjugate Vaccine in Premature infants. Pediatric Infectious Diseases Journal 2005;24(11):966-8.


Huo Z. Sinha R. McNeela EA. Borrow R. Giemza R. Cosgrove C. Heath PT. Mills KH. Rappuoli R. Griffin GE. Lewis DJ. Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan. Infection & Immunity 2005; 73(12):8256-65.


Haitham El Bashir, Paul T. Heath, Thomas Papa, Jens U Ruggeberg, Nik Johnson, Ruchi Sinha, Gail Balfour and Robert Booy. Antibody responses to meningococcal (groups A, C, Y and W135) polysaccharide diphtheria toxoid conjugate vaccine in children who previously received meningococcal C conjugate vaccine. Vaccine. 2006; 24:2544-9.


David M. Vu, Paul T. Heath, Noel D. McCarthy, Andrew J.Pollard and Dan M. Granoff. Effectiveness Analyses May Underestimate Protection of Infants after Group C Meningococcal Immunization. The Journal of Infectious Diseases 2006;194(2):231-7.


Paul Clarke, Michael J Robinson, Ijaz Ahmad, Alison R Bedford-Russell, Jane E Connell, Peter J Powell, Paul T Heath. Response of steroid-treated former preterm infants to a single dose of meningococcal C conjugate vaccine. Vaccine. 2006;24(16):3273-8.


Nik G Johnson, Jens U Ruggeberg, Gail F Balfour, Y Chen Lee, Helen Liddy, Diane Irving, Joanna Sheldon, Mary PE Slack, Andrew J Pollard, Paul T Heath. Reemergence of Haemophilus influenzae type b associated with reduced antibody and avidity responses after primary immunization with acellular pertussis-containing combination vaccines. Emerging Infectious Diseases 2006 Jun;12(6):937-41.


Conterno LO, Silva Filho CR, RŸggeberg JU, Heath PT. Conjugate vaccines for preventing meningococcal C meningitis and septicaemia. Cochrane Database Syst Rev. 2006 Jul 19;3:CD001834


Kohl KS, Ball L, Gidudu J, Hammer SJ, Halperin S, Heath P, Hennig R, Labadie J, Rothstein E, Schuind A, Varricchio F, Walop W; The Brighton Collaboration Local Reactions Working Group for Abscess at Injection Site. Abscess at injection site: Case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine. 2007 Aug 1;25(31):5821-38.


Jens U. Ruggeberg, Clare Collins, Paul Clarke, Nik Johnson, Ruchi Sinha, Neil Everest, John Chang, Elaine Stanford, Paul Balmer, Ray Borrow, Sarah Martin, Michael J. Robinson, E Richard Moxon, Andrew J. Pollard, Paul T. Heath. Immunogenicity and induction of immunological memory of the heptavalent pneumococcal conjugate vaccine in preterm UK infants. Vaccine. 2007 Jan 4;25(2):264-71.


Ladhani S, Slack PP, Heath PT, Ramsay ME. Changes in ascertainment of Hib and its influence on the estimation of disease incidence in the United Kingdom. Epidemiol Infect. 2007 Jul;135(5):861-7.


Patel SR, Ort’n M, Cohen BJ, Borrow R, Irving D, Sheldon J, Heath PT. Re-immunization with measles, tetanus, poliovirus, Haemophilus influenzae type b, meningococcal C and pneumococcal vaccines in children following hematopoietic stem cell transplantation. Clin Infect Dis. 2007 Mar 1;44(5):625-34.


Patel SR, Ort’n M, Cohen BJ, Borrow R, Irving D, Sheldon J, Heath PT. Reimmunization of children after completion of standard chemotherapy for acute leukemia. Clin Infect Dis. 2007 Mar 1;44(5):635-42.


Kohl KS, Walop W, Gidudu J, Ball L, Halperin S, Hammer SJ, Heath P, Hennig R, Rothstein E, Schuind A, Varricchio F; The Brighton Collaboration Local Reactions Working Group for Induration at or near Injection Site. Induration at or near injection site: Case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine. 2007 Aug 1;25(31):5839-57.


Halperin S, Kohl KS, Gidudu J, Ball L, Hammer SJ, Heath P, Hennig R, Labadie J, Rothstein E, Schuind A, Varricchio F, Walop W; The Brighton Collaboration Local Reaction Working Group for Cellulitis at Injection Site. Cellulitis at injection site: Case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine. 2007 Aug 1;25(31):5803-20


Kohl KS, Walop W, Gidudu J, Ball L, Halperin S, Hammer SJ, Heath P, Varricchio F, Rothstein E, Schuind A, Hennig R; The Brighton Collaboration Local Reaction Working Group for Swelling at or near Injection Site. Swelling at or near injection site: Case definition and guidelines for collection, analysis and presentation of immunization safety data. Vaccine. 2007 Aug 1;25(31):5858-74.


Roche A, Heath PT, Sharland M, Strachan D, Breathnach A, Haigh J, Young Y. Prevalence of nasopharyngeal carriage of pneumococcus in preschool children attending day care in London. Archives of Disease in Childhood 2007 Dec;92(12):1073-6.


S J C Cameron, G Allan, F Johnston, A Finn, PT Heath, R Booy. Severe complications of chickenpox in hospitalised children in the UK and Republic of Ireland. Archives of Disease in Childhood, 2007 Dec;92(12):1062-6.


Lee YC, Kelly D, Yu L, Slack M, Booy R, Heath PT, Siegrist C, Moxon ER, Pollard AJ. Haemophilus influenzae type b vaccine failure in children is associated with inadequate production of high quality antibody. Clin Infect Dis. 2008 Jan 15;46(2):186-92.


Sarah Y Oh; David Griffiths; Tessa John; Yeh C Lee; Lymee M Yu; Noel McCarthy; Paul T Heath; Derrick Crook; Mary Ramsay; E. Richard Moxon; Andrew J. Pollard. School-age children: a reservoir for continued circulation of Haemophilus influenzae type b in the UK. Journal of Infectious Diseases 2008 May 1;197(9):1275-81.

Fernando A, Heath PT, Menson E. Antimicrobial policies in British and Irish neonatal units. Journal of J Antimicrob Chemother. 2008 Mar;61(3):743-5.

Ladhani S, Heath PT, Ramsay ME, Slack MP. Changes in antibiotic resistance rates of invasive  Haemophilus influenzae isolates in England and Wales over the last 20 years. <http://www.ncbi.nlm.nih.gov/pubmed/18664478?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum> J Antimicrob Chemother.   2008 Oct;62(4):776-9.

Liz Schroeder, Stavros Petrou, Gail Balfour, Oya Edamma, Paul T. Heath. The economic costs of Group B Streptococcus (GBS) disease: prospective cohort study of infants with GBS disease in England. The European Journal of Health Economics 2009 Jul;10(3):275-85.

A local reaction at or near injection site: Case definition and guidelines for collection, analysis, and presentation of immunization safety data. Jane Gidudu, Katrin S. Kohl , Scott Halperin , Sandra Jo Hammer, Paul T. Heath , Renald Hennig, Bernard Hoet , Edward Rothstein , Anne Schuind, Frederick Varricchio , Wikke Walop, The Brighton Collaboration Local Reactions Working Group for A Local Reaction at or near Injection Site. Vaccine 2008 (in press).

Heath PT, Balfour GF, Tighe H, Verlander NQ, Lamagni TL, Efstratiou A; HPA GBS Working Group. Group B streptococcal disease in infants: a case control study. <http://www.ncbi.nlm.nih.gov/pubmed/19457879?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum> Arch Dis Child. 2009 Sep;94(9):674-80.

Ladhani S, Paul T Heath, Mary E Ramsay, Mary PE Slack, Elizabeth Kibwana, Andrew J Pollard, Robert Booy. Long-term immunological follow-up of children with Hib vaccine failure. CID 2009 (in press).

Ladhani, Shamez; Heath, Paul; Slack, Mary; McIntyre, Peter; Diez-Domingo, Javier; Campos Marqués, José; Dagan, Ron; Ramsay, Mary. Haemophilus influenzae serotype b conjugate vaccine failure in twelve countries with established national childhood immunisation programmes. Clinical Microbiology and Infection. 2009 (in press).

Vergnano S, Embleton ND, Collinson A, Menson E, Bedford Russell AR, Heath PT. Missed opportunities for preventing GBS infections. <http://www.ncbi.nlm.nih.gov/pubmed/19439431?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum>  Arch Dis Child Fetal Neonatal Ed. 2009 May 12

Cervicofacial nontuberculous mycobacterium lymphadenitis in children: is surgery always necessary? <http://www.ncbi.nlm.nih.gov/pubmed/19586666?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3> Harris RL, Modayil P, Adam J, Sharland M, Heath P, Planche T, Daya H. Int J Pediatr Otorhinolaryngol. 2009 Sep;73(9):1297-301^

Jessica M. Bate, Soonie R. Patel, Julia Chisholm,^ Paul T. Heath^. Immunisation practices of paediatric oncology and shared care oncology consultants: a United Kingdom survey. Pediatric Blood & Cancer. 2009 (in press).

Shamez Ladhani, Mary P.E. Slack, Paul T. Heath, Anne von Gottberg, Manosree Chandra, Mary E. Ramsay and EU-IBIS participants. Invasive Haemophilus influenzae disease in the post-vaccine era: data from European surveillance 1996-2006. Emerging Infectious Diseases 2010 (in press).

Ladhani S, Heath PT, Aibara RJ, Ramsay ME, Slack MP, Hibberd ML,Pollard AJ,Moxon ER,Booy R. Long-term complications and risk of other serious infections following invasive Haemophilus influenzae serotype b disease in vaccinated children. Vaccine 2010 (in press).

Baba Inusa, Nimze Gadong, Michele Afif, Sarah Arnott, Paul Heath, Grant Marais, Helen Payne, Paula Robertson, Olu Wilky, Mark Zuckerman, David C Rees. Pandemic influenza A (H1N1) virus infections in children with sickle cell disease. Blood 2010 (in press)

Conterno LO, Heath PT. <http://www.ncbi.nlm.nih.gov/pubmed/18535031?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum> Seroprotection against serogroup C meningococcal disease. BMJ. 2008 Jun 5

Patel SR, Chisholm JC, Heath PT. <http://www.ncbi.nlm.nih.gov/pubmed/18242320?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum> Vaccinations in children treated with standard-dose cancer therapy or hematopoietic stem cell transplantation. Pediatr Clin North Am. 2008 Feb;55(1):169-86

Soonie R Patel, Paul T Heath, Immunization in children with cancer, Paediatrics and Child Health (2008) (in press)

Shamez Ladhani, Fiona Neely, Paul Heath, Bernadette Nazareth, Richard Roberts, Mary P.E. Slack, Jodie McVernon, Mary E. Ramsay Recommendations for the prevention of secondary Haemophilus influenzae type b (Hib) disease.  Journal of Infection 2009 (in press).

Galiza EP, Heath PT. Improving the outcome of neonatal meningitis. <http://www.ncbi.nlm.nih.gov/pubmed/19333122?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum> Curr Opin Infect Dis 2009;22(3):229-34.

Galiza EP, Heath PT. Pertussis. Medicine <http://www.sciencedirect.com/science/journal/13573039>. Volume 37, Issue 12 <http://www.sciencedirect.com/science?_ob=PublicationURL&_tockey=%23TOC%2333054%232009%23999629987%231571198%23FLA%23&_cdi=33054&_pubType=J&view=c&_auth=y&_acct=C000047882&_version=1&_urlVersion=0&_userid=912075&md5=08882d41f63814ebb2a1e00a3605b882>, December 2009, Pages 635-637

Expediting clinical trials in a pandemic. <http://www.ncbi.nlm.nih.gov/pubmed/19903713?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1> Pollard AJ, Reiner A, John T, Sheasby E, Snape M, Faust S, Collinson A, Finn A, Heath PT, Miller E. BMJ. 2009 Nov 10;339:b4652.